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Analyzing association between low-density lipoprotein reduction by statin and adherence to medication using national health insurance service-national sample cohort (NHIS-NSC)
Journal of the Korean Data & Information Science Society 2017;28:1027-41
Published online September 30, 2017
© 2017 Korean Data & Information Science Society.

Kyu-Jin Kim1 · Chi-Hyuck Jun2 · Hyeseon Lee3 · Hun-Sung Kim4

123Department of Industrial and Management Engineering, Pohang University of Science and Technology
4Department of Medical Informatics, College of Medicine, The Catholic University of Korea
Correspondence to: Hyeseon Lee
Professor, Department of Industrial and Management Engineering, Pohang University of Science and Technology, Pohang 37673, Korea. E-mail : hyelee@postech.ac.kr
Co-Corresponding author: Hun-Sung Kim
Professor, Department of Medical Informatics, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea
Received September 6, 2017; Revised September 19, 2017; Accepted September 21, 2017.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Hyperlipidemia, the status of blood with high level of low-density lipoprotein cholesterol (LDL-C), is known as a main cause of coronary artery diseases such as myocardiac infarction or brain infarct. Statin is the representative prescription to hyperlipidemia and the effects of it depend on the patient’s individual conditions such as health-caring habits or adherence to medication. The main effect of statin is reducing LDL-C, which should reach the target range based on National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III) guideline. In this research, the reduction of LDLC and attainment to patient’s target range are considered effects of statin. The association between factors - individual conditions and adherence to medication of patients - and the effects of statin is analyzed with National Health Insurance Service-National Sample Cohort (NHIS-NSC).
Keywords : Adherence to medication, hyperlipidemia, low-density lipoprotein cholesterol, national sample cohort, statin